Endothelin-1 in Periodontal Diseases: A Mini-Review

نویسندگان

  • Waleed Khalid
  • Shuji Awano
چکیده

Endothlin-1 (ET-1) is a 21 amino acid peptide and is a potent vasoconstrictor produced by endothelial cells. It plays a role in the development of diseases such as hypertension and atherosclerosis. Reports have suggested the identification of ET-1 in chronic periodontitis and gingival overgrowth. Thus, there is a need to appraise the role of ET-1 in periodontal disease. Further research is needed to confirm its use as a biomarker and to incorporate endothelin-antagonists in periodontal therapy.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

New modalities for treatment of diabetic nephropathy: a mini review

Background and aims: Diabetic nephropathy (DN) is the most common cause of end-stage renal failure which could increase the risk of cardiovascular disease and morbidity and mortality in patients. The aim of this study was to investigate new modalities for treatment of diabetic nephropathy. Methods:This study was a mini-review research to investigate drugs that are used for DN treatment. Resul...

متن کامل

poor oral health and fertility problems: A narrative mini-review

Introduction: Recently, it has been recognized that oral infections, especially periodontitis might have effect on several systemic conditions. A possible role of oral diseases in sub-fertility and infertility was also has been suggested. The aim of this review was to evaluate the association between poor oral health and fertility problems. Methods: In this narrative review, authors used PUBMED...

متن کامل

Study of Porphyromonas gingivalis in periodontal diseases: A systematic review and meta-analysis

Background: The mouth cavity hosts various types of anaerobic bacteria including Porphyromonas gingivalis, which causes periodontal inflammatory diseases. P. gingivalis is a gram-negative oral anaerobe and is considered as a main etiological factor in periodontal diseases. Several studies have reported a relationship between P. gingivalis in individuals with periodontal diseases and a critical ...

متن کامل

Oral Health and Coronary Artery Disease, A Review Article

Atherosclerosis is the most common cause of myocardial infarction and ischemic stroke. Various risk factors have been identified for atherosclerosis. Recently, bacterial and viral organisms, which are involved in chronic inflammatory processes, have been also implicated in atherosclerosis development. Individuals with a prior history of periodontal diseases and/or tooth loss are considered to be...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015